Calcomp Digitizer?

"set up such an input tablet"

If it works like an ordinary pointing device (mouse / trackball / tablet), it should Just Work™ in LightBurn to move the cursor around and click-to-set points & nodes.
I’ve used a Huion tablet for freehand layout in LightBurn, but a trackball seems more suitable for precise work. Perhaps my hand isn’t steady enough for the fine resolution required to drop points exactly on target, but adjusting the ball produces better results.
For real precision, I feed coordinates & offsets directly into the Numeric Edits fields.