Cutting Mat Board?

I am sure you can cut it, but the edges will always burn some with any laser and I think you will end up with soot getting everywhere. For some things you can get it damp and the steam reduces the burn a bit, but not paper or cardboard that I have ever seen and colored paper will bleed when it gets wet.
Only maybe if everything is black or dark brown including the core of the mat board and you pretty much never touch the edges after they are cut…
Just my opinion, but I would not think it is likely to have a good outcome…